Pakistan News Service

Wednesday Apr 23, 2014, Jumada-al-thani 22, 1435 Hijri
Logo Logo
LATEST :
Pakistan News Home -> Health -> News Details

You are what daddy ate: study

16 December, 2013

PARIS: A father's diet influences the health of his offspring, according to a study published by French media that suggests men, like women, should plan to eat and live healthily in the run-up to conception.

Researchers led by Sarah Kimmins at McGill University in Montreal, Canada, looked at what happened when male lab mice had a diet that was poor in vitamin B9.

B9, also called folate, is present in green leafy vegetables, cereals, fruit and meat. Women often take folic acid supplements, before and during pregnancy, to reduce the risk of miscarriage and birth defects in their offspring.

But Kimmins' team were startled to find that male mice that had a B9-deficient diet also fathered mice with a higher rate of birth defects, compared to counterparts which had eaten sufficient folate.

"We were very surprised to see that there was an almost 30-percent increase in birth defects in the litters sired by fathers whose levels of folates were insufficient," said one of the team, Romain Lambrot.

"We saw some pretty severe skeletal abnormalities that included both cranio-facial and spinal deformities."

The problem, according to the investigators, lies in the sperm's epigenome, or the "switches" that turn genes -- the protein-making codes for life -- on and off.

This switchgear, influenced by diet or other life experiences, deregulates key genes during the embryo's development, according to their theory. If the findings in rodents also turn out to hold true for humans, there are important implications for men's diet, said Kimmins.

"Despite the fact that folic acid is now added to a variety of foods, fathers who are eating high-fat, fast-food diets or who are obese may not be able to use or metabolise folate in the same way as those with adequate levels of the vitamin," she said.

"Our research suggests that fathers need to think about what they put in their mouths, what they smoke and what they drink and remember they are caretakers of generations to come." The study appears in the journal Nature Communications.

End.

 What do you think about the story ? Leave your comments!

Heading (Optional)
Your Comments: *

Your Name:*
E-mail (Optional):
City (Optional):
Country (Optional):
 
 
Field marked(*) are mandatory.
Note. The PakTribune will publish as many comments as possible but cannot guarantee publication of all. PakTribune keeps its rights reserved to edit the comments for reasons of clarity, brevity and morality. The external links like http:// https:// etc... are not allowed for the time being to be posted inside comments to discourage spammers.

  Speak Out View All
Artilce 6 and Musharraf Trail
Blocking Nato supply line
  Quick Vote Show Results
Question: "In view of the current situation do you think Talks with Taliban should take place only within the ambit of Article 4 of Objectives Resolution that defines our Common Purpose i.e. PM/ President down to all Pakistanis to work till we achieve the rights of Democracy, Freedom, Tolerance and Social Justice for all Pakistanis:"
Yes
No
 
Candid Corner
Exclusive by
Lt. Col. Riaz Jafri (Retd)
Drone kills 15 'Qaeda', three civilians in Yemen: security
Senior journalist Hamid Mir hurt in Karachi attack
Suggested Sites