Pakistan News Service

Friday Oct 31, 2014, Muharram 7, 1436 Hijri
Logo Logo
LATEST :
Pakistan News Home -> Health -> News Details

Increase in rare childhood cancers linked to air pollution exposure

12 April, 2013

ISLAMABAD: Scientists from UCLA's Fielding School of Public Health have found a possible link between exposure to traffic-related air pollution and several childhood cancers.

The results of their study, led by Julia Heck, an assistant researcher in the school's epidemiology department and a member of UCLA's Jonsson Comprehensive Cancer Center - the first to examine air pollution from traffic and a number of rarer childhood cancers - were presented on April 9 in an abstract at the annual meeting of the American Association for Cancer Research in Washington, D.C.

For the study, the UCLA researchers utilized data on 3,950 children who were enrolled in the California Cancer Registry and who were born in the state between 1998 and 2007.

They estimated the amount of local traffic the children had been exposed to using California LINE Source Dispersion Modeling, version 4 (CALINE4).

Pollution exposure was estimated for the area around each child's home for each trimester of their mother's pregnancy and during their first year of life.

The estimates included information on gasoline and diesel vehicles within a 1,500-meter radius buffer, traffic volumes, roadway geometry, vehicle emission rates and weather.

Cancer risk was estimated using a statistical analysis known as unconditional logistic regression.

The researchers found that heightened exposure to traffic-related air pollution was associated with increases in three rare types of childhood cancer - acute lymphoblastic leukemia ( white blood cell cancer ), germ-cell tumors (cancers of the testicles, ovaries and other organs) and retinoblastoma (eye cancer), particularly bilateral retinoblastoma, in which both eyes are affected.

The pollution-exposure estimates were highly correlated across pregnancy trimesters and the first year of life, meaning that even in areas of high exposure, no particular period stood out as a higher-exposure time. This, the scientists said, made it difficult to determine if one period of exposure was more dangerous than any other.

"Much less is known about exposure to pollution and childhood cancer than adult cancers," Heck said.

"Our innovation in this study was looking at other, more rare types of childhood cancer, such as retinoblastoma, and their possible connection to traffic-related air pollution," she said.

Because these are rare diseases, Heck cautions that the findings need to be replicated in further studies.

End.

 What do you think about the story ? Leave your comments!

Heading (Optional)
Your Comments: *

Your Name:*
E-mail (Optional):
City (Optional):
Country (Optional):
 
 
Field marked(*) are mandatory.
Note. The PakTribune will publish as many comments as possible but cannot guarantee publication of all. PakTribune keeps its rights reserved to edit the comments for reasons of clarity, brevity and morality. The external links like http:// https:// etc... are not allowed for the time being to be posted inside comments to discourage spammers.

  Speak Out View All
Imran - Qadri long march
Artilce 6 and Musharraf Trail
  Quick Vote Show Results
Question: "In view of the current situation do you think Talks with Taliban should take place only within the ambit of Article 4 of Objectives Resolution that defines our Common Purpose i.e. PM/ President down to all Pakistanis to work till we achieve the rights of Democracy, Freedom, Tolerance and Social Justice for all Pakistanis:"
Yes
No
 
Candid Corner
Exclusive by
Lt. Col. Riaz Jafri (Retd)
Gullu Butt sent to prison for 11 years
Sweden becomes the first E.U. member to recognize the state of Palestine
Suggested Sites