Pakistan News Service

Saturday Nov 22, 2014, Muharram 29, 1436 Hijri
Logo Logo
LATEST :
Pakistan News Home -> Health -> News Details

Heart disease could be tied to dementia for older women

05 January, 2014

ISLAMABAD: Older women with a history of heart trouble were more likely to develop thinking and memory problems than those without heart disease, it was found in a new study.

Women who'd had a heart attack, in particular, were twice as likely to see declines in their thinking and memory skills, researchers found.

Doctors had already suspected such a link existed, lead author Dr. Bernhard Haring said.

"But our study provides new evidence on a broad scale including many different types of heart disease with a specific focus on postmenopausal women," he said.

Haring is based at the Comprehensive Heart Failure Center at the University of Würzburg in Germany.

He and his colleagues used data from a long-term study of more than 6,000 women ages 65 to 79.

Researchers asked the women if they had ever been diagnosed with any heart problems. They also gave them a test of brain function at the beginning of the study and then once every year.

None of the women had thinking and memory problems at the outset. Close to 900 reported having heart disease.

About eight years later, more than 400 women showed signs of cognitive decline or dementia. Women who said they'd had heart disease were 29 percent more likely to have cognitive problems than those without heart disease.

Women who'd had a heart attack had the highest risk of developing thinking and memory trouble, the researchers reported in the Journal of the American Heart Association.

Those with a history of bypass surgery or peripheral vascular disease - hardening of the arteries that bring blood to the legs and feet - were also at greater risk, Haring said.

But neither an abnormal heart rhythm nor heart failure was linked to a decline in brain function.

Regardless of whether women had heart disease, those with high blood pressure and diabetes had a higher risk of cognitive decline. But no link was seen with obesity.

The new study is important because of the sheer number of women involved, Dr. Richard O'Brien said. He is chairman of Neurology at Johns Hopkins Bayview Medical Center in Baltimore, Maryland, and wasn't involved in the research.

Understanding the connection between heart disease and dementia is important because heart disease is reversible but Alzheimer's disease is not, O'Brien said.

"Given that the number of individuals suffering from dementia is increasing in all developed countries, it is important and necessary to first investigate the reasons of why this is happening and to identify those particularly at risk and second to find measures on how to prevent and treat affected individuals," Haring said.

An ageing circulatory system could lead to worsening brain function in many ways, he said. Gradual buildup of plaque in the veins and arteries or inflammation may play a role, as could small bits of tissue death in the brain over time due to poor blood supply.

"Heart disease is more than just blocked arteries, it's an inflammatory process as well and also affects the turnover of brain endothelial cells, cerebrospinal fluid production (which washes away bad things in the brain) - lots of things," O'Brien said. "Which exactly is the most important nobody knows."

About 35 percent of people over age 80 have dementia, he noted.

Women with any kind of heart disease should see their doctor on a regular basis, Haring said.

"Cardiovascular risk factors such as hypertension and in particular diabetes should be managed adequately as these may provide a link between (heart disease) and worsening cognitive functioning over time," Haring said.

End.

 What do you think about the story ? Leave your comments!

Heading (Optional)
Your Comments: *

Your Name:*
E-mail (Optional):
City (Optional):
Country (Optional):
 
 
Field marked(*) are mandatory.
Note. The PakTribune will publish as many comments as possible but cannot guarantee publication of all. PakTribune keeps its rights reserved to edit the comments for reasons of clarity, brevity and morality. The external links like http:// https:// etc... are not allowed for the time being to be posted inside comments to discourage spammers.

  Speak Out View All
Imran - Qadri long march
Artilce 6 and Musharraf Trail
  Quick Vote Show Results
Question: "In view of the current situation do you think Talks with Taliban should take place only within the ambit of Article 4 of Objectives Resolution that defines our Common Purpose i.e. PM/ President down to all Pakistanis to work till we achieve the rights of Democracy, Freedom, Tolerance and Social Justice for all Pakistanis:"
Yes
No
 
Candid Corner
Exclusive by
Lt. Col. Riaz Jafri (Retd)
LHC tells Sharif family to pay Rs 3.5bn mark-up on loan
Osama's killer comes forward to reveal his name
Suggested Sites