Pakistan News Service

Saturday Aug 30, 2014, Zul-qaadah 4, 1435 Hijri
Logo Logo
LATEST :
Pakistan News Home -> Health -> News Details

Doctors May Screen Stool Samples for Cancer

18 May, 2013

ISLAMABAD: Doctors may soon be able to save lives by checking stool samples for DNA evidence of cancer, researchers said .

A new stool test could one day help spot colorectal cancer, one of the most common cancers in the industrialized world, which now can usually be detected only with uncomfortable invasive procedures.

Scientists have long been looking for telltale signs in the stools of cancer sufferers that would allow for a less invasive test. A team of researchers, writing in the British journal The Lancet, reported that they found such signs in DNA in the stools.

When detected at the earliest stage, colon cancer is nearly 100 percent curable, doctors say. Hannes M. Mueller, from Austria's Medical University in Innsbruck, and colleagues were able to distinguish stools of patients with colorectal cancer from those of healthy patients by examining chemical changes to DNA found in the stool.

A gene known as SFRP2 was more likely to have undergone a chemical process called "methylation" in the stools of cancer sufferers than in those of healthy individuals.

"To our knowledge, SFRP2 methylation represents one of the most sensitive markers for identifying colorectal cancer ... in stool samples," wrote Martin Winschwendter, the study's principle investigator.

He said it still remained to be seen whether a group of markers could be found that would identify cancer at an early stage from stool samples.

Exact Sciences Corp., a small Massachusetts company, does have a test called Pregen-Plus that isolates human DNA from stool samples for early detection of colorectal cancer. However, Pregen-Plus, which has been available in the United States since last August, looks at different markers than those cited by researchers in the Lancet report.

The Exact Sciences test has shown to be a more accurate detector of cancer than the common fecal occult blood test, which only determines the presence of blood in stool -- a possible indicator cancer, but one that could have other causes.

End.

 What do you think about the story ? Leave your comments!

Heading (Optional)
Your Comments: *

Your Name:*
E-mail (Optional):
City (Optional):
Country (Optional):
 
 
Field marked(*) are mandatory.
Note. The PakTribune will publish as many comments as possible but cannot guarantee publication of all. PakTribune keeps its rights reserved to edit the comments for reasons of clarity, brevity and morality. The external links like http:// https:// etc... are not allowed for the time being to be posted inside comments to discourage spammers.

  Speak Out View All
Imran - Qadri long march
Artilce 6 and Musharraf Trail
  Quick Vote Show Results
Question: "In view of the current situation do you think Talks with Taliban should take place only within the ambit of Article 4 of Objectives Resolution that defines our Common Purpose i.e. PM/ President down to all Pakistanis to work till we achieve the rights of Democracy, Freedom, Tolerance and Social Justice for all Pakistanis:"
Yes
No
 
Candid Corner
Exclusive by
Lt. Col. Riaz Jafri (Retd)
Speaker Ayaz Sadiq has only 25 PTI resignations
ANP fighting for parliament, not PM: Asfandyar
Suggested Sites