Pakistan News Service

Monday Nov 24, 2014, Safar 1, 1436 Hijri
Logo Logo
LATEST :
Pakistan News Home -> Health -> News Details

Dieting triggers chemical changes in the brain: Study

29 December, 2012

ISLAMABAD: Dieting makes people feel depressed because cutting out fatty foods alters their brain, a new study has claimed.

Scientists have found that ditching a high-fat diet triggers actual chemical changes in the brain that could make people enter a vicious cycle of poor eating.

Since fatty and sugary foods cause chemical changes before obesity even occurs, the University of Montreal researchers likened going on a diet to drug withdrawal.

"By working with mice, whose brains are in many ways comparable to our own, we discovered that the neurochemistry of the animals who had been fed a high fat, sugary diet were different from those who had been fed a healthy diet," Dr Stephanie Fulton said. "The chemicals changed by the diet are associated with depression. A change of diet then causes withdrawal symptoms and a greater sensitivity to stressful situations, launching a vicious cycle of poor eating," Fulton said.

The researchers fed one group of mice a low-fat diet and a high-fat diet to a second group over six weeks, monitoring how the different food affected the way the animals behaved.

Fat represented 11 per cent of the calories in the low-fat diet and 58 per cent in the high-fat diet, causing the waist size in the second group to increase by 11 per cent, which is not yet obese.

The relationship between rewarding mice with food and their resulting behaviour and emotions was then measured, and the brains of the mice were studied to see if there had been any changes.

Results showed mice that had been fed the higher-fat diet exhibited signs of being anxious - such as avoiding open areas - and their brains had been altered.

A molecule the researchers looked at was dopamine, which enables the brain to reward people with good feelings and encourages them to learn certain kinds of behaviour.

They found another molecule, CREB, involved in memory, which causes the production of dopamine, is more activated in the brains of the higher-fat mice.

"CREB is much more activated in the brains of higher-fat diet mice and these mice also have higher levels of corticosterone, a hormone that is associated with stress. This explains both the depression and the negative behaviour cycle," Fulton said.

End.

 What do you think about the story ? Leave your comments!

Heading (Optional)
Your Comments: *

Your Name:*
E-mail (Optional):
City (Optional):
Country (Optional):
 
 
Field marked(*) are mandatory.
Note. The PakTribune will publish as many comments as possible but cannot guarantee publication of all. PakTribune keeps its rights reserved to edit the comments for reasons of clarity, brevity and morality. The external links like http:// https:// etc... are not allowed for the time being to be posted inside comments to discourage spammers.

  Speak Out View All
Imran - Qadri long march
Artilce 6 and Musharraf Trail
  Quick Vote Show Results
Question: "In view of the current situation do you think Talks with Taliban should take place only within the ambit of Article 4 of Objectives Resolution that defines our Common Purpose i.e. PM/ President down to all Pakistanis to work till we achieve the rights of Democracy, Freedom, Tolerance and Social Justice for all Pakistanis:"
Yes
No
 
Candid Corner
Exclusive by
Lt. Col. Riaz Jafri (Retd)
LHC tells Sharif family to pay Rs 3.5bn mark-up on loan
Osama's killer comes forward to reveal his name
Suggested Sites